Introduction to research programmes
Biomaterials are being developed in response to clinical needs. Research includes work on new biomaterials for drug release, transfection, prosthetics and enhanced implant biocompatibility. Engineered surfaces and scaffolds are being developed for cell culture and tissue engineering.
Tissue engineering research at Sheffield is working towards a number of targets including of cartilage, nerve, bone, cornea, skin, urethra and oral muscosa. These are important for clinical applications, as well as providing proof-of-concept for engineering more complex tissues.
Devices, implants & bioreactors devices for dignity, prosthetics and implants.
Stem cells for bone, nerve, tendon, gene and therapeutics applications.
Imaging and analysis techniques used at Sheffield to analyse and evaluate engineered tissues, implant materials and prosthetics.
Computational systems biology takes data from cell biology and body imaging techniques to model prosthetic tissues and design heart valves and drug delivery systems. Increasingly it is also important for following complex interactions, such as signalling pathways within and between cells, and helping us to understand how tissues develop, and how best to engineer them for clinical use.